Medical

A Cure For The Common Cold Is On The Horizon

A Cure For The Common Cold Is On The Horizon

Whenever someone gets the common cold, the available remedies will only treat the symptoms and not the virus itself.

According to MedlinePlus, a fever of 100°F or higher, cough, fatigue, a runny nose, and a sore throat are symptoms that you already have the virus. Even if we grow immune, viruses evolve fast and the get resistant to drugs. Without the protein shield, the virus's genetic heart of RNA is exposed and vulnerable - and the virus can not replicate.

Viruses normally steal NMT from human cells and use it to create a protective shell around their genetic information, known as the capsid.

Millions of people every year also receive unnecessary antibiotic prescriptions from doctors for the common cold making it a major source of our growing antibiotic resistance problem. The team's findings were recently published in the journal Nature Chemistry.

Instead of attacking the virus, researchers at Imperial College London designed a drug that blocks a protein in the body's cells that cold viruses usually commandeer to self-replicate and spread.

The drug is also hypothetically effective in dealing with polio and foot and mouth disease, which have similar viruses to the common cold.




It took mere minutes for IMP-1088 to take effect on human lung cells in a laboratory trial.

"The common cold is an inconvenience for most of us, but can cause serious complications in people with conditions like asthma and [chronic obstructive pulmonary disease]". The lab tests on human cells showed that the molecule they used could effectively combat different strains of the virus.

The research team included the labs of Professor Roberto Solari and Professor Seb Johnston at Imperial's National Heart & Lung Institute, Dr Aurelie Mousnier from Imperial and Queen's University Belfast, structural biologists at the University of York, and colleagues at the Pirbright Institute.

This article has been republished from materials provided by Imperial College London.

The research showed that this molecule is over 100 times more potent than previous molecules targeting the protein in humans. Note: material may have been edited for length and content.


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