New study links body clock to mood disorders

New study links body clock to mood disorders

Measurements of people's rest-work cycles could be a useful tool for flagging and treating people at risk of major depression or bipolar disorders, the researchers concluded. This can be due to reduced activity during waking periods or increased activity during rest periods.

Mathematical modelling was used to investigate associations between low relative amplitude (reflecting greater activity during rest periods and/or daytime inactivity) and lifetime risk of mood disorder as well as wellbeing and cognitive function. They occur in plants, animals and throughout biology, and are fundamental for maintaining health in humans, particularly mental health and wellbeing.

They were also 9% less likely to describe themselves as happy (OR 0.91, 95% CI 0.90 to 0.93) and 9% more likely to describe themselves as often feeling lonely (OR 1.09, 95% CI 1.07 to 1.11).

They used wearable fitness-tracking devices to assess the physical activity of 90,000 people in the United Kingdom, and then compared the results with associated questionnaires looking at mood and mental health outcomes.

Circadian rhythms control functions including sleep patterns, body temperature, our immune systems and the release of hormones.

Researchers analysed activity data in more than 91,000 participants aged 37-73 from the UK Biobank general population cohort to obtain an objective measure of patterns of rest and activity rhythms.

The results held true even after adjusting for a wide range of influential factors including age, sex, lifestyle, education, body mass index, and childhood trauma.

A new study established a link between biological clock disruptions and increased risk for mental health issues.

Messing with your body clock - or circadian rhythms, if you prefer long words - seriously increases your risk of mood disorders, the University of Glasgow researchers found. "That's not a big surprise", said Dr. Daniel Smith, professor of psychiatry at the University of Glasgow and a leading author on the study.

People who disrupt their body clock - being active at night or inactive during the day - have a greater risk of developing mood disorders, according to a study in Britain.

They said the findings were "consistent with suggestions that disruption of circadian rhythms is a core feature of mood disorders".

This study adds to the evidence that good sleep at night and activity during the day is linked to better mental health.

The circadian rhythm disruptions were defined as an increased nighttime activity, decreased daytime activity, or both at the same time. It measured people's mood, activity levels and mental health problems at different times, with some mood measurements taken before activity levels and some afterwards.

Smith said, 'It's not just what you do at night, it's what you do during the day - trying to be active during the day and inactive in darkness, ' he said.

"So we need to think about ways to help people tune in to their natural rhythms of activity and sleeping more effectively".

Some researchers believe modern life may be the reason for this trigger.